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. 2020 May 6;22:105. doi: 10.1186/s13075-020-02190-3

Table 3.

Characteristics of the patients with axial spondyloarthritis stratified by calprotectin percentiles. All results are mean (with standard deviation), except those with an asterisk* which are median [with interquartile range], and those marked with a “§” which are number of patients (%). Abbreviations: BMI body mass index, CRP C-reactive protein, ESR erythrocyte sedimentation rate, BASDAI Bath Ankylosing Spondylitis Disease Activity Index, BASFI Bath Ankylosing Spondylitis Functional Index, ASDAS Ankylosing Spondylitis Disease Activity Score

Serum calprotectin quartile [μg/ml] 0–1.6 1.6–2.4 2.4–3.9 3.9–13 p value
n 113 113 112 113
Disease duration, years 10.4 (10.2) 8.5 (9.8) 9.9 (9.8) 10.6 (9.4) 0.37
Age years 45.9 (11.4) 44.4 (12.7) 43.0 (11.3) 42.7 (13.7) 0.20
Gender = male§ 62 (54.9) 62 (54.9) 67 (59.8) 77 (68.1) 0.03
BMI kg/m2 25.3 (4.7) 26.3 (4.8) 26.3 (5.4) 26.3 (4.7) 0.44
ESR mm/h* 6.0 [4.0, 11.5] 8.0 [4.0, 17.5] 8.0 [4.0, 16.0] 10.0 [4.0, 25.0] 0.01
CRP mg/l* 3.0 [1.0, 8.0] 2.0 [1.0, 8.0] 3.0 [1.0, 8.0] 4.0 [2.0, 13.0] < 0.01
BASDAI score 3.6 (2.3) 4.0 (2.4) 3.5 (2.4) 4.1 (2.3) 0.19
BASFI score 2.1 (2.3) 2.7 (2.6) 2.3 (2.3) 2.8 (2.5) 0.22
ASDAS score 2.1 (0.9) 2.4 (1.0) 2.2 (1.1) 2.7 (1.0) 0.01
ASDAS moderate/high§1 40/79 (50.6) 47/81 (58.0) 37/65 (56.9) 49/72 (68.1) 0.04
ASDAS remission§2 14/79 (17.7) 16/81 (19.8) 20/65 (30.8) 4/72 (5.56) 0.20
Physician global disease activity 1.9 (1.6) 2.4 (2.0) 2.2 (2.0) 2.6 (1.8) 0.02
Swollen joint count 0.4 (0.9) 0.6 (1.8) 0.4 (0.9) 0.3 (1.2) 0.46
Hip involvement§ 3 (2.7) 3 (2.7) 5 (4.5) 10 (8.8) 0.02
Enthesitis§ 32 (28.3) 38 (33.6) 40 (35.7) 36 (31.9) 0.68
Dactylitis§ 2 (1.8) 0 (0.0) 5 (4.5) 3 (2.7) 0.51

1Proportion of patients with an ASDAS score ≥ 2.1

2Proportion of patients with an ASDAS score < 1.3