Table 2.
The IC50 values of C. citratus essential oils on various lung cancer cell lines.
| Essential oilsa (μg/ml) | Wild type of EGFR and TKI-resistance | Mutation of EGFR and TKI-resistance | ||
|---|---|---|---|---|
| A549 | H1299 | H1650 | H1975 | |
| HCL | 3.84 ± 0.43 | 2.45 ± 0.21 | 6.24 ± 0.52 | 5.36 ± 0.27 |
| HCC | 3.77 ± 0.28 | 3.56 ± 0.40 | 6.81 ± 0.75 | 6.16 ± 0.54 |
| HLL | 1.73 ± 0.37 | 3.37 ± 0.18 | 7.89 ± 0.64 | 4.01 ± 0.30 |
| HLC | 4.50 ± 0.30 | 4.94 ± 0.47 | 8.71 ± 0.36 | 4.25 ± 0.53 |
| LTL | 4.98 ± 0.68 | 5.79 ± 0.27 | 6.52 ± 0.29 | 4.74 ± 0.07 |
| LTC | 4.40 ± 0.75 | 6.56 ± 0.39 | 8.36 ± 0.08 | 5.83 ± 0.25 |
| KDL | 4.25 ± 0.32 | 7.50 ± 0.93 | 6.15 ± 0.28 | 5.46 ± 0.93 |
| KDC | 5.28 ± 0.59 | 8.93 ± 0.50 | 4.86 ± 0.29 | 8.49 ± 0.68 |
| Camptothecinb | 0.48 ± 0.02 | 0.49 ± 0.05 | 0.42 ± 0.01 | 0.42 ± 0.05 |
aExperiments were carried out in triplicate; bpositive control.