Table 1. General characteristics of the study population.
Variables | Control (n=159) | EH (n=182) | P-value |
---|---|---|---|
Age, years | 60 (50, 67) | 64 (59, 72) | 0.0011 |
Male, % | 55.3 | 52.2 | 0.5612 |
FG, mmol/l | 5.12 (4.80, 5.63) | 5.19 (4.77, 5.90) | 0.3761 |
TC, mmol/l | 5.24 ± 0.98 | 4.42 ± 1.17 | <0.0013 |
TG, mmol/l | 1.26 (0.91, 1.84) | 1.25 (1.00, 1.73) | 0.5961 |
HDL-c, mmol/l | 1.25 ± 0.29 | 1.05 ± 0.27 | <0.0013 |
LDL-c, mmol/l | 3.31 ± 0.84 | 2.81 ± 1.05 | <0.0013 |
Creatinine | 69.35 (59.60, 80.11) | 79.28 (65.81, 101.23) | <0.0011 |
Homocysteine | 12.17 (10.66, 15) | 13.86 (11.64, 18.35) | 0.0021 |
Uric acid | 323.20 (282.73, 395.72) | 381.94 (300.51, 481.51) | <0.0011 |
PLT (×109/l) | 212.92 ± 55.18 | 205.74 ± 66.01 | 0.2843 |
PDW, % | 13.4 (11.8, 15.3) | 12.8 (11.5, 14.88) | 0.2431 |
MPV, fl | 11.00 (10.3, 11.9) | 10.90 (10.23, 11.80) | 0.6241 |
PCT | 0.24 ± 0.05 | 0.23 ± 0.06 | 0.1243 |
BMI | 23.58 ± 3.06 | 25.14 ± 3.64 | <0.0013 |
miR-202-3p | −1.71 ± 2.27 | 0.13 ± 1.94 | <0.0013 |
Smoking, % | 22.3 | 18.5 | 0.3942 |
Drinking, % | 8.9 | 20.2 | 0.0042 |
Family history of hypertension, % | 29.9 | 18.5 | 0.0152 |
Data are expressed as mean ± SD, median (25th, 75th quartiles) or percentages.
Abbreviations: MPV, mean platelet volume; PCT, plateletcrit; PDW, platelet distribution width; PLT, blood platelet count.
Mann–Whitney U test for the differences between EH patients and controls.
Chi-square test for the difference in the distribution frequencies between EH patients and controls.
Student’s t test for the difference between EH patients and controls.