Table 2.
Effect of flaxseed oil supplementation on fatty acids status of erythrocytes
| Variable | Flaxseed oil (n = 21) | Placebo (n = 19) | MD (95% CI), P value |
|---|---|---|---|
| LA (%) | |||
| Before | 14.53 (6.22) | 15.59 (8.48) | 1.32 (− 4.26 to 6.90), 0.632a |
| After | 9.68 (3.25) | 12.10 (3.94) | 2.89 (0.07 to 5.72), 0.045b |
| MD (95% CI), P valuec | − 4.84 (− 9.16 to − 0.53), 0.031 | − 3.49 (− 7.18 to 0.19), 0.062 | |
| AA (%) | |||
| Before | 13.59 (5.64) | 11.59 (6.87) | − 1.21 (− 6.07 to 3.65), 0.613a |
| After | 9.56 (1.40) | 8.75 (1.56) | − 1.06 (− 2.47 to 0.36), 0.135b |
| MD (95% CI), P valuec | − 4.03 (− 7.46 to − 0.60), 0.026 | − 2.84 (− 6.76 to 1.07), 0.143 | |
| ALA (%) | |||
| Before | 0.20 (0.12) | 0.21 (0.11) | 0.01 (− 0.07 to 0.10), 0.679a |
| After | 0.56 (0.24) | 0.22 (0.10) | − 0.35 (− 0.51 to − 0.20), < 0.001b |
| MD (95% CI), P valuec | 0.37 (0.23 to 0.51), < 0.001 | 0.004 (− 0.08 to 0.09), 0.925 | |
| EPA (%) | |||
| Before | 1.15 (0.60) | 1.08 (0.87) | − 0.28 (− 0.84 to 0.27), 0.301a |
| After | 1.06 (0.72) | 0.87 (0.50) | − 0.29 (− 0.96 to 0.37), 0.364b |
| MD (95% CI), P valuec | − 0.09 (− 0.51 to 0.32), 0.612 | − 0.21 (− 0.65 to 0.22), 0.305 | |
| DHA (%) | |||
| Before | 1.43 (0.87) | 1.24 (0.76) | − 0.20 (− 0.83 to 0.43), 0.520a |
| After | 1.36 (0.44) | 1.29 (0.46) | − 0.08 (− 0.52 to 0.36), 0.704b |
| MD (95% CI), P valuec | − 0.07 (− 0.80 to 0.65), 0.822 | 0.05 (− 0.35 to 0.45), 0.796 | |
Values are expressed as mean (SD)
LA linoleic acid, AA arachidonic acid, ALA α-linolenic acid, EPA eicosapentaenoic acid, DHA docosahexaenoic acid, MD mean difference
aIndependent samples t-test
bAdjusted for baseline values, weight differences, and energy and fat intake changes using the analysis of covariance (ANCOVA) test
cPaired-samples t-test