Table 3.
Logistic regression model predicting final HbA1C levels in 118 patients with hepatitis C and diabetes mellitus (n = 118).
| Covariate (1) | Reference variable (0) | Estimate | Chi square | P value |
|---|---|---|---|---|
| Age | — | -0.080 | 4.490 | 0.034∗ |
| Gender | Female | 0.015 | 0.000 | 0.975 |
| Race | Black | 0.413 | 0.560 | 0.453 |
| Viral load | — | -4.9e-8 | 0.460 | 0.497 |
| Genotype 1 | Non-1 | -0.104 | 0.080 | 0.772 |
| Moderate/severe chronic hepatitis | Minimal/mild chronic hepatitis | 0.474 | 0.960 | 0.326 |
| Baseline serum ALT level | — | -0.026 | 7.090 | 0.008∗ |
| Baseline serum AST level | — | 0.029 | 7.190 | 0.007∗ |
| Baseline BMI | — | -0.064 | 2.280 | 0.131 |
| Pretreatment HbA1C | — | 0.209 | 1.730 | 0.189 |
| Severe fibrosis or cirrhosis | No, mild, or significant fibrosis | 0.066 | 0.020 | 0.889 |
| Treatment with DAAs | No treatment | 1.609 | 25.12 | <0.0001∗ |
∗ P < 0.05. ALT: alanine aminotransferase; AST: aspartate aminotransferase; BMI: body mass index; DAAs: direct acting antiviral agents for HCV; HbA1C: hemoglobin A1C level (%); HCV: hepatitis C virus; P: probability.