Table 1.
The relationship between GLYR1 expression and CRC clinicopathological features
| No.of cases | Low | Medium | High | χ2 value | P-value | |
|---|---|---|---|---|---|---|
| Frequency | 221 (100%) | 44 (19.9%) | 64 (29.0%) | 113 (51.1%) | ||
| Age | ||||||
| Younger (< 60 years) | 118 (53.4%) | 24 (20.3%) | 36 (30.5%) | 58 (49.2%) | 0.427 | 0.808 |
| Older (> = 60 years)) | 103 (46.6%) | 20 (19.4%) | 28 (27.2%) | 55 (53.4%) | ||
| Gender | ||||||
| Male | 135 (61.1%) | 26 (19.3%) | 42 (31.1%) | 67 (49.6%) | 0.781 | 0.677 |
| Female | 86 (38.9%) | 18 (20.9%) | 22 (25.6%) | 46 (53.5%) | ||
| Position | ||||||
| Colon | 150 (67.9%) | 38 (25.3%) | 45 (30.0%) | 67 (44.7%) | 10.890 | 0.004 |
| Rectum | 71 (32.1%) | 6 (8.4%) | 19 (26.8%) | 46 (64.8%) | ||
| Tumor sise (maximum diameter) | ||||||
| < 5 cm | 106 (48.0%) | 8 (7.5%) | 34 (32.1%) | 64 (60.4%) | 19.726 | < 0.001 |
| > =5 cm | 115 (52.0%) | 36 (31.3%) | 30 (26.1%) | 49 (42.6%) | ||
| Tumor grade (diffrentiation) | ||||||
| G1 | 27 (12.2%) | 1 (4.8%) | 6 (28.6%) | 14 (66.7%) | 33.570 | < 0.001 |
| G2 | 173 (78.3%) | 27 (15.6%) | 51 (29.5%) | 95 (54.9%) | ||
| G3 | 21 (9.5%) | 16 (59.3%) | 7 (25.9%) | 4 (14.8%) | ||
| Invasive depth | ||||||
| Submucosal | 14 (6.4%) | 0 (0.0%) | 6 (42.9%) | 8 (57.1%) | 9.586 | 0.143 |
| Myometrium | 21 (9.5%) | 2 (9.5%) | 6 (28.6%) | 13 (61.9%) | ||
| Subserosal | 92 (41.6%) | 16 (17.4%) | 26 (28.3%) | 50 (54.3%) | ||
| Break the serosa | 94 (42.5%) | 26 (27.7%) | 26 (27.7%) | 42 (44.6%) | ||
| Mucinous component | ||||||
| Absent | 165 (74.7%) | 21 (12.7%) | 52 (31.5%) | 92 (55.8%) | 21.066 | < 0.001 |
| Present | 56 (25.3%) | 23 (41.1%) | 12 (21.4%) | 21 (37.5%) | ||
| Microsatellite instability | ||||||
| MSS | 164 (74.2%) | 7 (4.3%) | 48 (29.3%) | 109 (66.4%) | 107.823 | < 0.001 |
| MSI-L | 6 (2.7%) | 4 (66.6%) | 1 (16.7%) | 1 (16.7%) | ||
| MSI-H | 51 (23.1%) | 33 (64.7%) | 15 (29.4%) | 3 (5.9%) | ||
| Lymphatic metastasis | ||||||
| Negative | 131 (59.3%) | 27 (20.6%) | 41 (31.3%) | 63 (48.1%) | 1.268 | 0.530 |
| Positive | 90 (40.7%) | 17 (18.9%) | 23 (25.6%) | 50 (55.5%) | ||