Table 1.
Dose and fractionations by site with [secondary options in square brackets]
| Tumor Location | Description | Total Dose (Gy) | Number of fractions | Dose per fraction (Gy) | Frequency | |
|---|---|---|---|---|---|---|
| Lung | Tumors 5 cm or less surrounded by lung parenchyma | 48 [54] | 4 [3] | 12 [18] | Daily, or Every second day | |
| Within 2 cm of mediastinum or brachial plexus | 60 | 8 | 7.5 | Daily | ||
| Bone | Any bone | 35 Gy [24] | 5 [2] | 7 [12] | Daily | |
| Brain | Stereotactic lesions (no whole brain RT) | < 2 cm | 24 | 1 | 24 | Once |
| 2–3 cm | 18 | 1 | 18 | Once | ||
| 3–4 cm | 15 | 1 | 15 | Once | ||
| If whole brain treated, then simultaneous boost to each lesion | 35Gy to metastases 20 Gy whole brain (Opt) | 5 | 7 Gy to PTV | Daily | ||
| 4 Gy WBRT | ||||||
| Liver | 54 Gy | 3 | 18 | Every second day | ||
| Adrenal | 40 Gy | 5 | 8 | daily | ||
| Lymph Node/Soft Tissue | 40 Gy | 5 | 8 | daily | ||
RT – radiotherapy; WBRT – whole brain radiotherapy