Table 1.

Study visits of the PRE-EASE trial

	Study period
	Enrollment	Allocation	Post-allocation
Time points	Preoperative	0 day (d)	Surgery	2 h	4 h	8 h	1 d	2d	3d	1 week (w)	Discharged	2w	4w	6w	3 months (m)	6 m
Enrollment
Eligibility screening	X
Informed consent	X
Random allocation		X
Interventions
Betamethasone plus ropivacaine		X
Ropivacaine		X
Assessments
Baseline data	X	X	X
Intraoperative data			X
Cumulative butorphanol consumption					X	X	X	X
Patients with no butorphanol								X
Total PCA button press count								X
Time of first analgesia demand					X	X	X	X
VASM				X	X	X	X	X	X	X		X	X	X	X	X
VASR				X	X	X	X	X	X	X		X	X	X	X	X
PSS				X	X	X	X	X	X	X		X	X	X	X	X
PONV				X	X	X	X	X
RSS				X	X	X	X	X
WHOQOL-BREF	X															X
ODI	X												X	X	X	X
POSAS																X
AEs
Nausea				X	X	X	X
Vomiting				X	X	X	X
Gastritis				X	X	X	X
GI bleeding				X	X	X	X
Delayed wound healing				X	X	X	X