Table 4.

Adjusted associations between log₁₀-transformed serum PBB-153, ΣPCB₄, and ΣPBDE₃ levels and the main

Predictors	PBB-153 a,b Born before incident began (N=579)	PBB-153 a Born after incident began (N=244)	ΣPCB4 a,b,c (N=801)	ΣPBDE3 a,b,c (N=352)
	10β (95% CI)	10β (95% CI)	10β (95% CI)	10β (95% CI)
Sex	1.00	1.00	1.00	1.00
Female	2.27 (1.81, 2.83)*	1.24 (0.81, 1.89)	1.41 (0.98, 2.04)	1.11 (0.86, 1.44)
Male
Sampling age (year)	1.03 (1.02, 1.04)*	1.07 (1.04, 1.10)*	1.04 (1.04, 1.05)*	1.01 (1.00, 1.03)*
Sampling age × sex
Sampling age × female	-	-	1.00	-
Sampling age × male			0.99 (0.99, 1.00)*
Serum lipids (mg/dL)d	1.14 (1.02, 1.27)*	0.94 (0.76, 1.16)	1.02 (0.96, 1.08)	0.96 (0.83, 1.11)
Exposure groups
Other residents	1.00		1.00e
Chemical workers	2.85 (1.93, 4.21)*		0.83 (0.65, 1.07)	1.00e-f
Family of chemical workers	2.05 (1.49, 2.84)*	-	1.00 (0.82, 1.22)	-
Farm/food family	2.68 (2.08, 3.44)*		1.02 (0.88, 1.18)	1.19 (0.80, 1.76)

Abbreviation: N, sample number of the model; 10^β, exponentiated β-coefficients represent the multiplicative change in serum levels for a one-unit change or comparing to the reference group; CI, confidence interval.

^aThe measurements below LOD were imputed by a lognormal probability distribution and maximum likelihood estimation.

^bPBB-153 and ΣPBDE₃ models were adjusted for sex, sampling age, serum lipids, and exposure groups; ΣPCB₄ model was adjusted for sex, sampling age, interaction of sex and sampling age, serum lipids, and exposure groups.

^cΣPCB₄ was calculated by adding PCB-118, 138, 153, 180; ΣPBDE₃: PBDE-47, 99, 100.

^dSerum lipids were centered around the mean and scaled to one standard deviation (SD): 1 SD = 211, 208, 211, 184 mg/dL for the PBB-153 (born before), PBB-153 (born after), ΣPCB₄, and ΣPBDE₃ models.

^eThe reference group combines the other residents and the people born after the incident began.

^fThe PBDE measurements were not available for chemicals workers (N=0) or family of chemical workers (N=1).

^*P-value < 0.05.