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. 2020 Jan 13;2020:7819321. doi: 10.1155/2020/7819321

Table 1.

Review of published cases of aplastic anemia after thymectomy.

Authors Ref. Sex/age Treatment for thymoma Interval between thymoma and AA Progress of blood disorder Associated diseases Treatment for AA Effect
Kobayashi et al. [4] F/63 TMT + RT 4 years ITP ⟶ AA ND Splenectomy + CyA E
Dinçol et al. [5] M/38 TMT 3 months AA ND CyA + ATG + mPSL + G-CSF E
Ritchie et al. [2] M/50 TMT + CT + RT 1 year AA Myasthenia gravis mPSL + CyA + ATG E
Park et al. [3] F/61 TMT 16 months AA ND CyA E
Maslovsky et al. [6] M/42 TMT + CT 12 months PRCA + AT ⟶ AA Myasthenia gravis ND ND
Bajel et al. [7] M/67 TMT 6 months AA ND CyA + ATG E
de Castro et al. [8] M/69 TMT 3 years AA ND CyA E
F/59 TMT + RT 2 years AA ND CyA + PDN NE
Simkins et al. [9] F/61 CT + TMT 3 months PRCA + AT ⟶ AA ND ATG + mPSL + CyA ⟶ SCT NE/E
Dahal et al. [10] M/63 TMT + CT + RT More than 3 years PRCA + AT ⟶ AA ND CyA ND
Present case M/53 TMT 3 years AT ⟶ AA ND CyA + PDN ⟶ SCT NE

Ref.: reference; AA: aplastic anemia; age: age at diagnosis of AA; TMT: thymectomy; CT: chemotherapy; RT: radiotherapy; CyA: cyclosporin A; ITP: immune thrombocytopenia purpura; ATG: antithymocyte globulin; PDN: prednisone; mPSL: methylprednisolone; ND: not described; NE: not effective; E: effective; PRCA: pure red cell aplasia; AT: amegakaryocytic thrombocytopenia; AA: aplastic anemia; G-CSF: granulocyte-colony stimulating factor; SCT: stem cell transplantation.