Table 2.

Validated viral elimination when processing fibrinogen: Omrix process

Step		Log kill or removal
	Virus:	HIV‐1	BVDV	PRV	HAV	CPV
	Model for:	HIV	HCV	HBV	HAV	Parvovirus B19
	Enveloped virus?:	Yes	Yes	Yes	No	No
Cryoprecipitation + Al(OH) treatment		ND	ND	ND	1.5	1.5
S/D treatment		>4.4*	>4.4†	>4.4†	ND	0
Pasteurization		>4.4‡	>5.5‡	ND	>5.8‡	1.3
	Sum:	>8.8	>9.9	>4.0	>7.3	2.8

^* No infectivity after 5 minutes. Treatment is for 4 hours.

^† No infectivity after 10 minutes, the first time point taken.

^‡ 9 to 10 hours were required to achieve reported kills. Treatment is for 10 hours.

Al(OH) = aluminum hydroxide; CPV = canine parvovirus; ND = not done.