Table 5.

Maintenance of clotting time and plasma coagulation factor activity after PCT *

Coagulation parameter	Reference range†	Pre‐PCT	Post‐PCT	Post/pre (% retention)
PT (n = 14)	11.1‐13.5	11.2 ± 0.3 sec	11.6 ± 0.3 sec	1.0 ± 0.1 sec‡
APTT (n = 14)	23.0‐35.0	26.8 ± 1.4 sec	29.1 ± 1.7 sec	4.3 ± 1.8 sec‡
Fibrinogen (n = 91)	167‐379	290 ± 40 mg/dL	209 ± 36 mg/dL	72 ± 5
FII (n = 59)	71‐127	96 ± 11 IU/dL	85 ± 11 IU/dL	88 ± 4
FV (n = 91)	77‐153	130 ± 23 IU/dL	119 ± 19 IU/dL	92 ± 7
FVII (n = 91)	58‐166	123 ± 32 IU/dL	95 ± 20 IU/dL	78 ± 6
FVIII (n = 91)	67‐235	157 ± 35 IU/dL	115 ± 28 IU/dL	73 ± 7
F IX (n = 91)	63‐143	108 ± 21 IU/dL	88 ± 16 IU/dL	82 ± 4
FX (n = 59)	66‐134	100 ± 13 IU/dL	86 ± 11 IU/dL	86 ± 3
FXI (n = 91)	62‐142	103 ± 22 IU/dL	87 ± 18 IU/dL	86 ± 5
FXIII (n = 26)	NA	110 ± 11 IU/dL	102 ± 10 IU/dL	93 ± 3
VWF:RCo (n = 12)	NA	114 ± 44 IU/dL	111 ± 41 IU/dL	97 ± 8

^* Results are reported as meant ± SD. n = number of replicates (treated plasma units) done for each parameter. (A higher number of replicates was performed for a basic testing panel, with additional parameters included in a subset of studies.) IU/dL = International Units/deciliter.

^† The reference range was calculated from the mean ± 2 SD of untreated, conventional plasma.

^‡ For PT and PTT, the effect of PCT was calculated by subtracting the pre‐PCT values from the post‐PCT values.