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. Author manuscript; available in PMC: 2021 Mar 23.
Published in final edited form as: Dev Cell. 2020 Mar 23;52(6):699–713.e11. doi: 10.1016/j.devcel.2020.02.011

Figure 7. Model.

Figure 7.

(A) pS22-Lamin A/C binds to putative enhancers near transcriptionally active genes.

(B) In progeria fibroblasts, gains of pS22-Lamin A/C-binding sites in abnormal locations accompany transcription of genes relevant to progeria phenotypes.