Table 3.
Univariate and multivariate analysis for OS in gastric cancer patients
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95%CI) | P value | HR (95%CI) | P value | |
| Gender | 0.742 (0.505–1.091) | 0.129 | ||
| Age | 1.270 (0.916–1.761) | 0.152 | ||
| Pathological differention | 1.191 (0.909–1.562) | 0.205 | ||
| Lymph nodes metastasis | 5.119 (3.296–7.952) | < 0.001 | 1.646 (0.864–3.135) | 0.130 |
| TNM stage | 3.147 (2.385–4.151) | < 0.001 | 3.564 (1.321–9.618) | 0.012 |
| Borrmann type | 1.433 (1.238–1.658) | < 0.001 | 0.980 (0.808–1.187) | 0.834 |
| Tumor size | 3.587 (2.559–5.028) | < 0.001 | 1.958 (1.349–2.842) | < 0.001 |
| Body mass index | 0.884 (0.619–1.264) | 0.500 | ||
| Anemia status | 1.512 (1.071–2.134) | 0.019 | 0.971 (0.676–1.394) | 0.872 |
| CEA | 1.686 (1.155–2.462) | 0.007 | 1.422 (0.959–2.107) | 0.080 |
| CA199 | 1.648 (1.106–2.455) | 0.014 | 1.043 (0.689–1.579) | 0.842 |
| FPR | 2.499 (1.794–3.483) | < 0.001 | 1.595 (1.072–2.373) | 0.021 |
| FAR | 2.343 (1.673–3.280) | < 0.001 | 1.236 (0.829–1.842) | 0.299 |
| FFC score | 1.704 (1.446–2.009) | < 0.001 | 1.414 (1.189–1.683) | < 0.001 |
OS overall survival; HR hazard ratio; CI confidence interval; CEA carcinoembryonic antigen; CA199 carbohydrate antigen 199; FPR fibrinogen-to-prealbumin ratio; FAR fibrinogen-to-albumin ratio; FFC FPR-FAR-CEA