Table 4.
– MVA of the parameters which were significant in UVA
| MVA | HR | 95% CI | P-value |
|---|---|---|---|
| Age | |||
| 65–69.9 | Reference | 0.002 | |
| 70–74.9 | 1.179 | 0.704–1.972 | 0.532 |
| 75–79.9 | 1.53 | 0.892–2.626 | 0.123 |
| > 80 years | 2.878 | 1.651–5.017 | < 0.001 |
| MGMT | |||
| methylated | Reference | ||
| unknown or non-methylated | 1.91 | 1.147–3.180 | 0.013 |
| KPS | |||
| 90–100% | Reference | 0.005 | |
| 70–80% | 0.85 | 0.534–1.351 | 0.491 |
| 50–60% | 1.949 | 1.104–3.439 | 0.021 |
| 10–40% | 4.433 | 0.92–21.352 | 0.063 |
| EOR | |||
| GTR | Reference | 0.275 | |
| STR | 1.331 | 0.855–2.072 | 0.205 |
| Biopsy | 1.567 | 0.868–2.830 | 0.136 |
| Motor deficits after surgery | |||
| no motor deficit | Reference | ||
| any motor deficit | 1.117 | 0.727–1.715 | 0.615 |
| Aphasia after surgery | |||
| no aphasia | Reference | ||
| aphasia | 1.466 | 0.907–2.370 | 0.118 |
Abbreviations: MVA Multivariate analysis, HR Hazard ratio, CI Confidence interval, KPS Karnofsky Performance Scale, MGMT O6-Methylguanine DNA-methyl transferase, EOR Extent of resection, STR Subtotal resection, GTR Gross total resection