Table 1. Table describing the rates of L1Hs insertion validation by binned average number of sequencing reads. The percentage of successfully validated novel non-ref L1Hs per read bin was used to calculate the number of predicted true positive novel non-ref L1Hs per bin. The calculated total true positive per read bin is the sum of the predicted true positive novel non-ref L1Hs and the total number of detected known non-ref and ref L1Hs per bin. The calculated percent true positive per bin is calculated as the total true positive for bin, divided by the sum of the number of detected novel non-ref L1Hs, number of detected known non-ref L1Hs and number of detected ref L1Hs. The cumulative percent true positive is calculated as the percentage of true positive L1Hs insertions having at least the average number of sequencing reads for that bin and above.

	novel non-ref L1Hs					known non-ref L1Hs	ref L1Hs	Calculated total true positive per bin	Calculated % true positive per bin	Cumulative % true positive (per bin and above)
Avg. # of reads	Successfully validated	Validations attempted	% Validated	total # detected per bin	Predicted true positive	total # detected per bin	total # detected per bin
≥1,000	32	44	72.7	460	334	227	465	1026	89.1	89.1
500-999	16	41	39.0	186	73	43	90	206	64.6	83.8
250-499	13	40	32.5	320	104	28	67	199	48.0	75.9
100-249	6	36	16.7	876	146	34	77	257	26.0	58.8

Table 1. Validation of putative Ta subfamily L1Hs insertions.