Figure 5.

Comparison of the effects of rapamycin on the consumption of oxygen (blue) and the production of carbon dioxide (pink) during the presence (w¹¹¹⁸) and absence (Sirt4white⁺¹) of the Sirt4 gene. (A) Mitochondrial haplotypes grouped by strains. (B) Haplotypes grouped by species of mtDNA. Error bars represent the 95% confidence interval. The number inside the bars represents the mean respiratory quotient (RQ): volume of CO₂/volume of O₂. All values were normalized to the reference sample (OreR w¹¹¹⁸ in standard treatment).