. 2020 Mar 9;10(5):1599–1612. doi: 10.1534/g3.120.401174

Table 1. Parametric analyses were performed for each comparison in this table. P-values are presented as raw and corrected for multiple comparisons using the Holm-Bonferroni method. For effect sizes, Hedges’ g correction was applied at the 0.95 confidence level, and the variances were pooled for each pair-wise comparison. Regression diagnostics (sample sizes, normality, group variances, etc) can be accessed from File S2. The abbreviations represent the following: wt= wildtype mtDNA haplotypes outlined in Figure 1A, w¹¹¹⁸= mtDNA haplotypes that express Sirt4 but are knockouts of the white gene, Sirt4^white+1= mtDNA haplotypes with the deletion of Sirt4. Std.= standard treatment, Rapa= rapamycin treatment, D. mel= D. melanogaster, D. sim= D. simulans.

ID#					Raw p-value	Holm	Hedge G	Magnitude
1	Std.	OreR	D. mel	w¹¹¹⁸ vs. Sirt4^white+1	0.0374	0.448	0.517	medium
2	Std.	Zim53	D. mel	w¹¹¹⁸ vs. Sirt4^white+1	0.485	1	0.28	small
3	Std.	sm21	D. sim	w¹¹¹⁸ vs. Sirt4^white+1	0.36	1	−0.368	small
4	Std.	si1	D. sim	w¹¹¹⁸ vs. Sirt4^white+1	0.0407	0.448	−1.15	large
5	Rapa	OreR	D. mel	w¹¹¹⁸ vs. Sirt4^white+1	0.42	1	0.197	negligible
6	Rapa	Zim53	D. mel	w¹¹¹⁸ vs. Sirt4^white+1	0.0536	0.526	0.804	large
7	Rapa	sm21	D. sim	w¹¹¹⁸ vs. Sirt4^white+1	0.405	1	0.335	small
8	Rapa	si1	D. sim	w¹¹¹⁸ vs. Sirt4^white+1	0.84	1	0.0919	negligible
9	w¹¹¹⁸	OreR	D. mel	Std. vs. Rapa	0.000018	0.000288	1.13	large
10	w¹¹¹⁸	Zim53	D. mel	Std. vs. Rapa	0.284	1	0.432	small
11	w¹¹¹⁸	sm21	D. sim	Std. vs. Rapa	0.405	1	0.335	small
12	w¹¹¹⁸	si1	D. sim	Std. vs. Rapa	0.498	1	0.332	small
13	Sirt4^white+1	OreR	D. mel	Std. vs. Rapa	0.00341	0.0512	0.74	medium
14	Sirt4^white+1	Zim53	D. mel	Std. vs. Rapa	0.0526	0.526	0.808	large
15	Sirt4^white+1	sm21	D. sim	Std. vs. Rapa	0.0237	0.307	0.958	large
16	Sirt4^white+1	si1	D. sim	Std. vs. Rapa	0.00376	0.0526	1.65	large
17	wt	C167.4	D. sim	Std. vs. Rapa	0.00917	0.0275	−0.693	medium
18	wt	C167.4	D. sim	Std. vs. Starvation	0.866	0.866	−0.044	negligible
19	wt	C167.4	D. sim	Rapa vs. Starvation	0.0154	0.0309	0.653	medium
20	wt	Zim53	D. mel	Std. vs. Rapa	0.000669	0.00201	1.6	large
21	wt	Zim53	D. mel	Std. vs. Starvation	0.00312	0.00624	1.34	large
22	wt	Zim53	D. mel	Rapa vs. Starvation	0.104	0.104	−0.668	medium
23	wt	OreR	D. mel	Std. vs. Rapa	0.00884	0.0265	1.84	large
24	wt	OreR	D. mel	Std. vs. Starvation	0.0261	0.0521	1.39	large
25	wt	OreR	D. mel	Rapa vs. Starvation	0.0812	0.0812	−1.09	large
26	wt	sm21	D. sim	Std. vs. Rapa	0.491	0.52	−0.282	small
27	wt	sm21	D. sim	Std. vs. Starvation	0.26	0.52	0.466	small
28	wt	sm21	D. sim	Rapa vs. Starvation	0.039	0.117	0.865	large
29	wt	si1	D. sim	Std. vs. Rapa	0.148	0.295	0.837	large
30	wt	si1	D. sim	Std. vs. Starvation	0.00414	0.0124	1.97	large
31	wt	si1	D. sim	Rapa vs. Starvation	0.352	0.352	0.521	medium
32	Std.		w1118	D. mel vs. D. sim	0.205	1	0.523	medium
33	Std.		Sirt4^white+1	D. mel vs. D. sim	0.0178	0.161	−0.658	medium
34	Rapa		w1118	D. mel vs. D. sim	0.718	1	0.0948	negligible
35	Rapa		Sirt4^white+1	D. mel vs. D. sim	0.971	1	−0.00939	negligible
36	w¹¹¹⁸		D. mel	Std. vs. Rapa	0.0000251	0.000302	0.93	large
37	w¹¹¹⁸		D. sim	Std. vs. Rapa	0.242	1	0.369	small
38	Sirt4^white+1		D. mel	Std. vs. Rapa	0.000432	0.00432	0.765	medium
39	Sirt4^white+1		D. sim	Std. vs. Rapa	0.000212	0.00234	1.27	large
40	Std.		D. mel	w¹¹¹⁸ vs. Sirt4^white+1	0.0388	0.31	0.438	small
41	Std.		D. sim	w¹¹¹⁸ vs. Sirt4^white+1	0.0406	0.31	−0.675	medium
42	Rapa		D. mel	w¹¹¹⁸ vs. Sirt4^white+1	0.0898	0.539	0.358	small
43	Rapa		D. sim	w¹¹¹⁸ vs. Sirt4^white+1	0.459	1	0.226	small