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. Author manuscript; available in PMC: 2020 May 6.
Published in final edited form as: Antiviral Res. 2017 Oct 31;148:20–31. doi: 10.1016/j.antiviral.2017.10.021

Figure 2. Viral load in respiratory tract of immunocompetent and immunosuppressed mice inoculated with influenza B viruses.

Figure 2.

Immunocompetent and immunosuppressed (DEX+CP-treated) BALB/c mice were anesthetized with isoflurane and inoculated intranasally with 102 TCID50/mouse (A, B) or 105 50 TCID50/mouse (C) of influenza PH/13 or BR/08 virus. Virus titers were determined in the lungs and nasal turbinates of mice (n = 3/group) at 3, 6, 10, and 16 dpi by TCID50 assays in MDCK cells. The bars represent the mean virus titers ± SDs in mouse nasal turbinates (A) and lungs (B, C). *P < 0.05, **P < 0.01, and ***P< 0.001 for comparisons of immunocompetent and immunosuppressed mice by one-way ANOVA with Bonferroni’s multiple comparison post-test.