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. Author manuscript; available in PMC: 2020 May 6.
Published in final edited form as: Antiviral Res. 2017 Oct 31;148:20–31. doi: 10.1016/j.antiviral.2017.10.021

Figure 3. Lymphocyte and neutrophil counts in immunocompetent and immunosuppressed mice inoculated with influenza B viruses.

Figure 3.

Immunocompetent and immunosuppressed (DEX+CP-treated) BALB/c mice were anesthetized with isoflurane and inoculated intranasally with 102 TCID50/mouse of influenza PH/13 or BR/08 virus. Blood was collected from uninfected control (PBS-treated) mice and from DEX+CP-treated uninfected and virus-inoculated mice (n = 5/group) by the retro-orbital route at −1, 3, 6, 10, 13, 17, and 24 dpi. Total lymphocyte (A), neutrophil (B), CD4+ cell (C), CD8+ cell (D), CD19+ cell (E), and NK cell (F) counts were determined with an automatic cell counter, and lymphocyte populations were differentiated by flow cytometry. Bars represent the mean values ± SDs. *P < 0.05, **P < 0.01, and ***P < 0.001 for comparisons of immunocompetent and immunosuppressed mice one-way ANOVA with Bonferroni’s multiple comparison post-test.