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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: J Mol Endocrinol. 2020 Jan;64(1):R21–R43. doi: 10.1530/JME-19-0105

Figure 2.

Figure 2

The major steroid biosynthetic pathways of the human adrenal gland. 3β HSD2, 3β-hydroxysteroid dehydrogenase/Δ5−4 isomerase, type, also called hydroxy-delta-5-steroid dehydrogenase, 3β- and steroid delta isomerase 2 (HSD3B2 gene); DHEA, dehydroepiandrosterone; DHEA-S, dehydroepiandrosterone-sulfate; P450c11, cytochrome P450c11 (steroid11 β-hydroxylase), also called Cytochrome P450 Family 11 Subfamily B Member 1 (CYP11B1 gene); P450c11AS, cytochrome P45011AS (aldosterone synthase), also called Cytochrome P450 Family 11 Subfamily B member 2 (CYP11B2 gene); P450c17, cytochrome P450c17 is the single enzyme mediating both 17α-hydroxylase/17,20 lyase activities, also called Cytochrome P450 Family 17 Subfamily A Member 1 (CYP17A1 gene); P450c21, cytochrome P450c21 (steroid 21-hydroxylase), also called Cytochrome P450 Family 21 Subfamily A Member 2 (CYP21A2 gene); P450scc, cytochrome P450scc side chain cleavage enzyme, also called Cytochrome P450 Family 11 Subfamily A Member 1 (CYP11A1 gene); StAR, steroidogenic acute regulatory protein (STAR gene); ST2A1, bile salt sulfotransferase 2A1/dehydroepiandrosterone sulfotransferase also called Sulfotransferase Family 2A Member 1 (SULT2A1 gene).