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. Author manuscript; available in PMC: 2020 May 6.
Published in final edited form as: Mol Cell Endocrinol. 2016 Oct 24;456:2–8. doi: 10.1016/j.mce.2016.10.024

Table 1.

miRNA involved in overall organs/body growth regulation

miRNA Species Proposed effect on growth Molecular target(s) Reference
miR-8/ miR200 Drosophila Promotes growth by increasing PI3K activation USH/FOG2 (Hyun et al. 2009)
miR-200 Zebrafish Suppresses growth by targeting GH-IGF-I signaling GH, GHR, IGF2a (Jing et al. 2015)
miR-9a Drosophila Suppresses growth by targeting insulin signaling sNPFR1/NPY2R (Suh et al. 2015)
miR-1/ miR-133 Mouse Suppresses cardiac hypertrophy RohA, Cdc42, Nelf-A/WHSC2 (Care et al. 2007)
let-7 Mouse Suppresses growth by regulating glucose metabolism and insulin sensitivity Myc, Kras, Igf2bp1, Hmga2 (Zhu et al. 2010)
(Frost & Olson 2011)
miR-29 Mouse Suppresses organs growth by targeting a genetic program Igf1, Mest, Igfbp1 (Kamran et al. 2015)