Figure 2.

Downregulated expression of circ_103809 suppresses cell proliferation and promotes cell apoptosis in breast cancer cell lines. (A) Cell proliferation ability was determined by CCK-8 assay. (B) Colony formation assay was employed for detecting cell proliferation. (C) Flow cytometric analysis was performed to detect the apoptotic rates in transfected cells. (D) Cell cycle progression was detected by flow cytometric analysis in transfected groups. Data are presented as the mean ± SD of three independent experiments. *P<0.05; **P<0.01; ***P<0.001; CCK-8, cell counting kit-8.