Table III.

Univariate regression and multivariate survival model of prognostic covariates in patients with clear cell renal carcinoma (Cox regression).

Clinicopathologic variables	Hazard ratio (95% CI)	P-value
Univariate analysis
Age (≥55 vs. <55)	1.58 (0.98–2.56)	0.060
Sex (male vs. female)	1.01 (0.66–1.54)	0.951
T (T3/T4 vs. T1/T2)	1.82 (1.47–2.25)	<0.001
N (N1 vs. N0)	2.93 (1.52–5.67)	0.001
M (M1 vs. M0)	4.07 (2.63–6.30)	<0.001
Grade (G3/G4 vs. G1/G2)	1.62 (1.29–2.04)	<0.001
Stage (III/IV vs. I/II)	1.92 (1.54–2.34)	<0.001
AGAP2-AS1	1.85 (1.48–2.33)	<0.001
Multivariate analysis
T (T3/T4 vs. T1/T2)	1.41 (0.62–3.25)	0.412
N (N1 vs. N0)	1.24 (0.62–2.49)	0.548
M (M1 vs. M0)	2.22 (1.32–3.73)	0.003
Grade (G3/G4 vs. G1/G2)	1.67 (1.01–2.75)	0.045
Stage (III/IV vs. I/II)	1.48 (0.58–3.75)	0.409
AGAP2-AS1	1.57 (1.21–2.03)	0.001