Table 2.
Phase | Chimp X283 | Chimp X286 | Chimp X317 |
---|---|---|---|
I | 103.5 CID50 † HBV | 104.5 CID50 HCV | 105.5 CID50 HBV |
II | 104.5 CID50 HCV | 104.5 CID50 HBV | 104.5 CID50 HCV |
In each phase of the study, after transfusion with treated PLT concentrates, the animals were followed for a 6‐month period for development of serologic, biochemical, molecular, and clinical signs of viral infection or disease.
The infectivity of HBV and HCV is expressed in chimpanzee infectious dose (CID50).