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. 2020 Apr 29;11:715. doi: 10.3389/fimmu.2020.00715

Table 1.

Module characteristics after WGCNA analysis of the hepatic transcriptomes including individuals challenged intramammary with E. coli or S. aureus and unchallenged controls.

Module name Spearman correlation between module eigengene and. infection categorya p_valuea N genes in moduleb N DEGs E. colic Proportion of DEGs E. colid N DEGs S. aureuse Proportion of DEGs S. aureusf
Turquoise −0.76 7.31E-09 6,067 4,067 0.67 1148 0.19
Darkred −0.51 5.94E-04 71 50 0.70 9 0.13
Pink −0.49 1.05E-03 406 216 0.53 37 0.09
Red −0.41 7.83E-03 553 102 0.18 37 0.07
Darkorange −0.40 9.83E-03 59 11 0.19 4 0.07
Royalblue −0.33 3.27E-02 72 61 0.85 52 0.72
Steelblue 0.32 3.95E-02 37 11 0.30 0 0.00
Brown 0.35 2.29E-02 2,436 653 0.27 503 0.21
Gray 0.43 5.40E-03 685 57 0.08 44 0.06
Cyan 0.44 4.01E-03 182 30 0.16 23 0.13
Darkturquoise 0.51 7.00E-04 65 42 0.65 29 0.45
Midnightblue 0.51 6.77E-04 171 89 0.52 63 0.37
Tan 0.54 2.49E-04 197 84 0.43 36 0.18
Green 0.61 2.21E-05 1,001 515 0.51 178 0.18
Blue 0.67 1.31E-06 4,875 3,586 0.74 485 0.10
Magenta −0.30 5.29E-02 258 49 0.19 26 0.10
Salmon −0.29 6.81E-02 188 32 0.17 2 0.01
Darkgrey 0.28 7.33E-02 61 18 0.30 15 0.25
Purple 0.27 8.42E-02 235 31 0.13 25 0.11
Saddlebrown 0.25 1.08E-01 53 16 0.30 6 0.11
Yellow −0.24 1.36E-01 1,751 753 0.43 678 0.39
Darkgreen 0.22 1.58E-01 69 1 0.01 12 0.17
Skyblue −0.17 2.77E-01 55 5 0.09 0 0.00
Lightyellow 0.15 3.57E-01 80 17 0.21 12 0.15
Black 0.14 3.98E-01 436 68 0.16 76 0.17
White −0.13 4.18E-01 58 4 0.07 12 0.21
Lightcyan 0.09 5.60E-01 145 10 0.07 15 0.10
Grey60 0.08 6.34E-01 96 42 0.44 90 0.94
Orange 0.07 6.54E-01 59 0 0.00 3 0.05
Lightgreen 0.03 8.74E-01 91 19 0.21 15 0.16
Greenyellow 0.00 9.90E-01 211 9 0.04 40 0.19
a

p-value for spearman correlation between module eigengene and infection category by sample;

b

Number of genes included in the respective module;

c

Number of DEGs (padj < 0.05) between E. coli challenged and control animals;

d

Proportion of genes in the respective module that are differentially expressed between E. coli challenged and control animals (modules with a proportion in the highest quartile indicated in red);

e

Number of DEGs (padj <0.05) between S. aureus challenged and control animals;

f

Proportion of genes in the respective module that are differentially expressed between S. aureus challenged and control animals (modules with a proportion in the highest quartile indicated in red).