Table 3.

Top 25 significantly enriched Ingenuity canonical pathways in the hepatic transcriptome comparing S. aureus challenged to non-challenged cows (NaN, no activation score).

Ingenuity canonical pathways	–log (p-value)	Ratio	z-score
Epithelial adherens junction signaling	6.62E00	2.23E-01	NaN
ILK signaling	6.13E00	1.96E-01	−3.33
Axonal guidance signaling	5.87E00	1.53E-01	NaN
Germ cell-sertoli cell junction signaling	5.73E00	1.99E-01	NaN
Integrin signaling	5.42E00	1.82E-01	−4.23
Acute myeloid leukemia signaling	4.83E00	2.29E-01	−2.98
Sertoli cell-sertoli cell junction signaling	4.76E00	1.83E-01	NaN
RhoGDI signaling	4.51E00	1.8E-01	3.02
Hepatic fibrosis/hepatic stellate cell activation	4.51E00	1.78E-01	NaN
IL-8 signaling	4.41E00	1.74E-01	−4.70
Breast cancer regulation by Stathmin1	4.33E00	1.71E-01	NaN
ERK/MAPK signaling	4.28E00	1.72E-01	−1.71
Actin cytoskeleton signaling	4.18E00	1.65E-01	−4.56
PTEN signaling	4.11E00	1.98E-01	3.27
Fcγ receptor-mediated phagocytosis in macrophages and monocytes	4.11E00	2.12E-01	−4.15
Signaling by Rho family GTPases	3.93E00	1.57E-01	−4.80
Remodeling of epithelial adherens junctions	3.74E00	2.32E-01	NaN
Chronic myeloid leukemia signaling	3.67E00	1.98E-01	NaN
Reelin signaling in neurons	3.62E00	2.07E-01	NaN
Ephrin receptor signaling	3.62E00	1.69E-01	−3.92
VEGF signaling	3.49E00	1.93E-01	−2.98
FAK signaling	3.46E00	1.96E-01	NaN
CDK5 signaling	3.40E00	1.94E-01	−0.45
Tight junction signaling	3.38E00	1.68E-01	NaN
Adipogenesis pathway	3.36E00	1.78E-01	NaN