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A, Core body temperature of adult BAT cKO females is significantly higher than control female littermates, especially during the dark phase when mice are most active (n = 9–12/group). B, C, BAT gene expression, in particular Cox8b, in BAT cKO females is increased versus controls (n = 8–10/group). D, E, Mean BAT and eWAT weights in adult BAT cKO females versus WT control littermates (n = 5–6/group). *P < .05, **P < .01, #P = .06
