Table 1. The top listed differentially-methylated CpG sites between KEAP1-mutated and wild-type LUAD patient samples.
| Hypomethylated CpG sites | Hypermethylated CpG sites | ||||||
| CpG name | Gene symbol | Delta Beta | P value | CpG name | Gene symbol | Delta Beta | P value |
| cg10880599 | GPX2 | -0.38 | 1.60E-10 | Cg25693302 | NEDD4L | 0.275 | 3.2488E-11 |
| cg04909257 | PGD | -0.36 | 3.11E-09 | Cg06632214 | IFITM1 | 0.259 | 2.0889E-05 |
| cg04806177 | MSRB1 | -0.35 | 1.94E-07 | Cg02370667 | NECAB2 | 0.241 | 2.7964E-07 |
| cg23230478 | ACOT7 | -0.348 | 7.81E-08 | Cg15733882 | NEDD4L | 0.231 | 2.1958E-10 |
| cg00926657 | MAFG | -0.343 | 2.79E-09 | Cg22167353 | NECAB2 | 0.229 | 3.7118E-07 |
| cg03331715 | TXNRD1 | -0.3437 | 5.91E-09 | Cg00474080 | HCG21 | 0.222 | 3.5719E-05 |
| cg02731193 | GCLC | -0.340 | 7.64E-08 | Cg15245625 | NEDD4L | 0.220 | 3.6348E-12 |
| cg19648686 | AKR1C1 | -0.333 | 5.60E-09 | Cg00225623 | SPATA13 | 0.214 | 2.6977E-06 |
| cg19648686 | AKR1C2 | -0.333 | 5.60E-09 | Cg04579966 | SPATA13 | 0.213 | 4.7484E-05 |
| cg09643186 | GPX2 | -0.330 | 1.78E-09 | Cg14186816 | NEDD4L | 0.212 | 2.8999E-11 |
| cg26155983 | GPX2 | -0.321 | 5.74E-08 | Cg13656752 | STK10 | 0.210 | 1.6346E-06 |
| cg09489844 | MAFG | -0.320 | 2.31E-09 | Cg03030717 | TBC1D30 | 0.203 | 0.00037491 |
| cg18484212 | SRXN1 | -0.310 | 1.30E-06 | Cg08781140 | MYO15B | 0.202 | 0.00014414 |
| cg23012192 | SQSTM1 | -0.305 | 1.07E-06 | cg19378330 | ABCC2 | 0.201 | 9.8216E-05 |
| cg20372666 | HK1 | -0.285 | 8.62E-10 | ||||
| cg04020792 | ATP2A2 | -0.277 | 2.02E-05 | ||||
| cg19509829 | ATP2A2 | -0.268 | 4.97E-06 | ||||
| cg14420550 | RP11-146I2.1 | -0.262 | 2.11E-07 | ||||
| cg18496841 | DLGAP2 | -0.254 | 6.94E-07 | ||||
| cg01189072 | CDK11B | -0.250 | 4.45E-05 | ||||
| cg05116443 | DNAJC5 | -0.249 | 2.58E-06 | ||||