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. 2020 Apr 21;12(8):7163–7182. doi: 10.18632/aging.103067

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Copyright © 2020 Bai et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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The linkage disequilibrium (LD) patterns of SNPs in ADD3 (A) and GPC1 (B). Haplotype blocks in ADD3 and GPC1 were defined according to the default method of Haploview. The numbers in the boxes are the pairwise correlation coefficient r² between respective SNPs. r² values of 1 represent complete LD, r² values greater than 0.8 represent strong evidence of LD, r² values of 0.2 – 0.8 represent inconclusive LD, and r² less than 0.2 represent negligible evidence of LD The r² value between rs6750380 and rs6707262 of was 0.98.