Table 3. Genotype distributions of ADD3 associated SNPs (rs17095355, rs10509906 and rs2501577) and GPC1 SNPs (rs6750380 and rs6707262) in BA patients and healthy controls.
SNP | Genotype | Genotype distribution N (%) | P value | ||||
Case | Control | Genotype | Dominant | Recessive | |||
rs17095355 | TT | 76(22.8) | 275(16.5) | 1.15×10-5 | 4.34×10-6 | 5.77×10-3 | |
TC | 177(53.2) | 771(46.3) | |||||
CC | 80(24.0) | 619(37.2) | |||||
rs10509906 | CC | 11(3.3) | 98(5.9) | 2.46×10-3 | 8.57×10-4 | 0.058 | |
CG | 93(27.9) | 584(35.1) | |||||
GG | 229(68.8) | 981(59.0) | |||||
rs2501577 | GG | 66(19.8) | 262(15.7) | 5.88×10-4 | 1.39×10-4 | 0.066 | |
GA | 177(53.2) | 770(46.2) | |||||
AA | 90(27.0) | 633(38.0) | |||||
rs6750380 | GG | 69(20.7) | 263(15.8) | 0.078 | 0.218 | 0.028 | |
GA | 151(45.3) | 777(46.7) | |||||
AA | 113(33.9) | 624(37.5) | |||||
rs6707262 | GG | 71(21.2) | 263(15.8) | 0.043 | 0.203 | 0.014 | |
GA | 150(45.0) | 780(46.9) | |||||
AA | 112(33.6) | 621(37.3) |
SNP: Single Nucleotide Polymorphism.