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. 2020 Apr 21;12(8):7163–7182. doi: 10.18632/aging.103067

Table 6. Gene-gene interaction models contribution to BA risk by GMDR analysis.

Number of factors Best model a Training accuracy Testing accuracy CVC Chi2 P value OR(95% CI)
1 rs17095355 0.5663 0.5637 10/10 10.4962 0.0012 1.89(1.28-2.78)
2 rs7577243-rs17095355 0.5782 0.5216 6/10 12.8256 0.0003 1.94(1.35-2.79)
3 rs11125609-rs7577243-rs17095355 0.6072 0.5713 10/10 23.2364 <0.0001 2.41(1.68-3.46)

a. The best model was referred to as the one with the maximum testing accuracy and maximum cross-validation consistency (CVC). GMDR: generalized multifactor dimensionality reduction; OR: odds ratio; CI: confidence interval. Rs17095355, rs7577243 and rs11125609 were on ADD3, GPC1 and EFEMP1, respectively.