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. 2020 Apr 20;12(8):6756–6773. doi: 10.18632/aging.103036

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Copyright © 2020 Cui et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Docetaxel-resistant HSC-3 (HSC-3DR) cells exhibited increased cell viability and inhibited apoptosis. (A) Cell viability in response to different concentrations of DTX in tongue squamous cell carcinoma cell lines was determined by CCK8 assays. (B) Cell viability of HSC-3 and HSC-3DR cells in response to different concentrations of DTX was determined by CCK8 assays. (C) The morphology of HSC-3 and HSC-3DR cells (scale bars = 50 μm). (D) Apoptosis of HSC-3 and HSC-3DR cells was determined by flow cytometry. (E) Invasion ability of HSC-3 and HSC-3DR cells was determined by Transwell assays (scale bars = 50 μm). (F) Migration ability of HSC-3 and HSC-3DR cells was determined by Transwell assays (scale bars = 50 μm). Data are presented as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.