| GO term |
Genes |
Fold enrichment |
p-value |
| GO:0051415~interphase microtubule nucleation by interphase microtubule organizing center |
Tubgcp4, Tubgcp5, Tubgcp3, Tubgcp2 |
574.0317 |
2.31E-08 |
| GO:0007020~microtubule nucleation |
Tubgcp4, Tubgcp5, Tubgcp3, Tubgcp2 |
215.2619 |
6.42E-07 |
| GO:0032508~DNA duplex unwinding |
Xrcc6, Rad50, Wrn, Mre11a |
191.3439 |
9.34E-07 |
| GO:0051298~centrosome duplication |
Tubgcp4, Tubgcp5, Tubgcp3, Tubgcp2 |
156.5541 |
1.76E-06 |
| GO:0007126~meiotic nuclear division |
Tubgcp4, Tubgcp5, Tubgcp3, Tubgcp2 |
143.5079 |
2.31E-06 |
| GO:0090307~mitotic spindle assembly |
Tubgcp4, Tubgcp5, Tubgcp3, Tubgcp2 |
98.40544 |
7.40E-06 |
| GO:0031122~cytoplasmic microtubule organization |
Tubgcp4, Tubgcp5, Tubgcp3, Tubgcp2 |
95.67196 |
8.07E-06 |
| GO:0006302~double-strand break repair |
Xrcc6, Rad50, Wrn, Mre11a |
54.66969 |
4.40E-05 |
| GO:0000226~microtubule cytoskeleton organization |
Tubgcp4, Tubgcp5, Tubgcp3, Tubgcp2 |
35.87698 |
1.55E-04 |
| GO:0000723~telomere maintenance |
Xrcc6, Rad50, Wrn |
67.97744 |
7.98E-04 |
| GO:0006974~cellular response to DNA damage stimulus |
Xrcc6, Sirt1, Rad50, Wrn, Mre11a |
10.25057 |
0.001035 |
| GO:0006310~DNA recombination |
Xrcc6, Rad50, Wrn |
30.38992 |
0.003927 |
| GO:0031860~telomeric 3' overhang formation |
Rad50, Mre11a |
430.5238 |
0.004417 |
| GO:0006281~DNA repair |
Xrcc6, Rad50, Wrn, Mre11a |
10.83079 |
0.00492 |
| GO:0000731~DNA synthesis involved in DNA repair |
Sirt1, Wrn |
215.2619 |
0.008816 |
| GO:0032206~positive regulation of telomere maintenance |
Rad50, Mre11a |
172.2095 |
0.011009 |
| GO:0000722~telomere maintenance via recombination |
Rad50, Wrn |
156.5541 |
0.012103 |
| GO:0033674~positive regulation of kinase activity |
Rad50, Mre11a |
143.5079 |
0.013196 |
| GO:0031954~positive regulation of protein autophosphorylation |
Rad50, Mre11a |
95.67196 |
0.019732 |
| GO:0046597~negative regulation of viral entry into host cell |
Rad50, Mre11a |
86.10476 |
0.021902 |
| GO:0006303~double-strand break repair via nonhomologous end joining |
Xrcc6, Mre11a |
82.00454 |
0.022985 |
| GO:0043066~negative regulation of apoptotic process |
Sirt1, Mre11a, Ddx3x, Myo18a |
6.085142 |
0.023396 |
| GO:0071480~cellular response to gamma radiation |
Xrcc6, Wrn |
71.75397 |
0.026227 |
| GO:0010667~negative regulation of cardiac muscle cell apoptotic process |
Sirt1, Hspa8 |
66.23443 |
0.028383 |
| GO:2001243~negative regulation of intrinsic apoptotic signaling pathway |
Ddx3x, Opa1 |
63.78131 |
0.029459 |
| GO:0071479~cellular response to ionizing radiation |
Eef1d, Sirt1 |
55.55146 |
0.033753 |
| GO:0006418~tRNA aminoacylation for protein translation |
Eprs, Vars |
47.83598 |
0.039095 |
| GO:0007346~regulation of mitotic cell cycle |
Sirt1, Rad50 |
46.54311 |
0.04016 |
| GO:0051276~chromosome organization |
Rad50, Mre11a |
45.3183 |
0.041223 |
| KEGG Term |
Genes |
Fold Enrichment |
p-value |
| mmu03450: Non-homologous end-joining |
Mre11a, Rad50, Xrcc6 |
148.4615 |
1.43E-04 |
| mmu03440: Homologous recombination |
Mre11a, Rad50 |
45.95238 |
0.039206 |
