Table 5.
Comparison of ‘Mistik Score’ and Modified Centor Score
| Sensitivity (%) | Specificity (%) | PPVa (%) | NPVb (%) | LR+c | LR− | |
|---|---|---|---|---|---|---|
| Mistik Score variables | ||||||
| Absence of headache | 45.8 | 62.4 | 48.1 | 60.2 | 1.22 | 0.87 |
| Stuffy nose | 71.1 | 56.0 | 55.1 | 71.8 | 1.61 | 0.52 |
| Sneezing | 55.4 | 74.3 | 62.2 | 68.6 | 2.16 | 0.60 |
| Temperature (≥37.5°C) | 30.1 | 68.5 | 35.1 | 63.4 | 0.95 | 1.02 |
| Absence of tonsillar exudate and/or swelling | 63.9 | 51.4 | 50.0 | 65.1 | 1.31 | 0.70 |
| Mistik Score | 60.2 | 72.5 | 62.5 | 70.5 | 2.19 | 0.55 |
| Modified Centor Score variables | ||||||
| Absence of cough | 77.5. | 56.4 | 20.7 | 94.5 | 1.77 | 0.39 |
| Tonsillar exudate and/or swelling | 82.5 | 57.2 | 22.1 | 95.7 | 1.92 | 0.30 |
| Fever (>38.0°C) | 16.3 | 92.3 | 23.6 | 88.2 | 2.11 | 0.90 |
| Anterior cervical lymphadenopathy | 66.3 | 69.5 | 24.2 | 93.3 | 2.17 | 0.48 |
| Ages 3–14 | 46.4 | 69.0 | 47.0 | 68.5 | 1.50 | 0.78 |
| Modified Centor Score | 62.9 | 78.5 | 40.1 | 90.3 | 2.93 | 0.47 |
aPPV = positive predictive value.
bNPV = negative predictive value.
cLR = likelihood ratio.