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. 2020 Apr 24;16(4):e1008360. doi: 10.1371/journal.ppat.1008360

Fig 3. Epithelial RAR signaling promotes IFNγ response to mediate pathogen clearance.

Fig 3

(A) Schematic representation of IFNγ feedback in stopΔIEC mice during Salmonella infection. Mice were intraperitoneally injected with 10 μg of IFNγ at 0 hpi and 48 hpi. Bacterial burden in (B) fecal and (C) mesenteric lymph nodes at 72 hrs post Salmonella infection in stopflox, stopΔIEC and stopΔIEC + IFNγ mice. One-way ANOVA was used for statistical analysis. **P<0.01, ***P<0.005.