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. 2020 Mar 17;10(3):e034226. doi: 10.1136/bmjopen-2019-034226

Table 4.

Factors associated with LDL-C level in age groups by sex

Variables B (95% CI) P value
Men ≤60 yo
n=87152; mean age:41.2±9.9 yo; mean LDL-C:2.59±0.82 mmol/L
Age 0.006 (0.005~0.007) <0.001
Glucose 0.045 (0.039~0.052) <0.001
BMI 0.108 (0.088~0.126) <0.001
Inactive lifestyle 0.021 (0.011~0.033) 0.001
Current smoker / /
Current drinker / /
Men ≥61 yo
n=10903; mean age:69.5±6.9 yo; mean LDL-C:2.59±0.82 mmol/L
Age −0.008 (−0.010~−0.006) <0.001
Glucose 0.045 (0.031~0.059) <0.001
BMI 0.064 (0.032~0.096) <0.001
Inactive lifestyle 0.101 (0.097~0.119) <0.001
Current smoker 0.023 (0.017~0.028) <0.001
Current drinker 0.007 (0.004~0.011) <0.001
Women ≤60 yo
n=64195; mean age:40.0±9.9 yo; mean LDL-C:2.44±0.72 mmol/L
Age 0.021 (0.020~0.021) <0.001
Glucose 0.111 (0.102~0.121) <0.001
BMI 0.086 (0.068~0.102) <0.001
Inactive lifestyle / /
Women ≥61 yo
n=5849; mean age:68.6±6.4 yo; mean LDL-C:2.72±0.82 mmol/L
Age −0.013 (−0.017~−0.010) /
Glucose / /
BMI 0.056 (0.024~0.088) 0.001
Inactive lifestyle / /

B is a coefficient indicating a one-unit increase in an independent variable in multivariable linear logic regression analyses. “/" indicates that a variable was not significantly associated with LDL-C level in a given model.

BMI, body mass index; LDL-C, low-density lipoprotein cholesterol; yo, years old.