Skip to main content
. 2020 May 6;157:104866. doi: 10.1016/j.phrs.2020.104866

Table 3.

Table reports the comparison of several features (hematological indication, safety, cost) in different hematological drugs that might have a role in the COVID-19. Abbreviations: MPN = chronic myeloproliferative neoplasms; MAS = macrophage activation syndrome; CML = chronic myeloid leukemia; ALL = acute lymphoblastic leukemia; GIST = stromal gastro-intestinal tumor; GVHD = graft-versus-host disease; LNH = non Hodgkin’s lymphoma; MM = multiple myeloma.

Ruxolitinib Imatinib Dasatinib Nilotinib Bosutinib Ibrutinib Begelomab IFN
Drug os os os os os os IV os
formulation
Clinical use in
GVHD XX X X X XX XX
Use in MPNs CML CML CML CML CLL GVHD CML
hematological MAS ALL ALL ALL MCL MPN
diseases GIST LNH
MM
Infection rate 20 % 5% 11 % 17 % 4% 71 % 10 % na
Estimated ++ + + + + +++ +++ +
costs