Table 2.
Fold-change in ABC transporter expression in the presence of chorioamnionitis in the preterm human placenta. *p<0.05. Fold-change is calculated by the ratio between PTDC and PTD relative expression. A fold-change > 1.0 indicates increased expression; fold-change < 1.0 indicates decreased expression; and fold-change = 0 indicates no change in relative expression
| ABCA Gene | Fold Change | ABCB Gene | Fold Change | ABCC Gene | Fold Change | ABCD Gene | Fold Change | ABCE Gene | Fold Change |
|---|---|---|---|---|---|---|---|---|---|
| ABCA1 | 1.01 | ABCB1 | 1.61* | ABCC1 | 1.23 | ABCD1 | 0.86 | ABCE1 | 1.18 |
| ABCA2 | 0.96 | ABCB2 | 1.06 | ABCC2 | 1.52* | ABCD2 | 0.81 | ||
| ABCA3 | 1.17 | ABCB3 | 1.00 | ABCC3 | 0.95 | ABCD3 | 1.35 | ||
| ABCA4 | 2.32 | ABCB4 | 1.64 | ABCC4 | 1.13 | ABCD4 | 1.11 | ||
| ABCA5 | 0.86 | ABCB5 | 0.67 | ABCC5 | 1.21 | ||||
| ABCA6 | 0.94 | ABCB6 | 1.35 | ABCC6 | 2.10 | ||||
| ABCA7 | 0.81 | ABCB7 | 1.23 | ABCC7 | 0.91 | ABCF | Fold | ABCG | Fold |
| ABCA8 | 0.77 | ABCB8 | 1.11 | ABCC8 | 1.6 | Gene | Change | Gene | Change |
| ABCA9 | 0.83 | ABCB9 | 1.47* | ABCC9 | 1.41 | ABCF1 | 1.26 | ABCG1 | 1.00 |
| ABCA10 | 0.62 | ABCB10 | 0.99 | ABCC10 | 1.06 | ABCF2 | 1.26* | ABCG2 | 1.72* |
| ABCA11 | 0.91 | ABCB11 | 1.21 | ABCC11 | 0.60 | ABCF3 | 1.00 | ABCG4 | 0.10 |
| ABCA12 | 0.99 | ABCC12 | 0.84 | ||||||
| ABCA13 | 0.82 | ABCC13 | 0.93 |