Table 3:
Replication of Association between HER2* status and Indigenous American ancestry in Colombian and Mexican breast cancer patients, N=616
| Covariates | Subtype | N | OR | 95% CI | P-value |
|---|---|---|---|---|---|
| Country | HER2− | 460 | Ref. | ||
| HER2+ | 156 | 1.26 | 1.08–1.49 | 0.004 | |
| Age dx + Afr + Country | HER2− | 460 | Ref. | ||
| HER2+ | 156 | 1.27 | 1.07–1.52 | 0.006 |
Age dx: age at diagnosis; Afr: African genetic ancestry proportion.
Colombia ER/PR+ HER2– 231, ER/PR+ HER2+ 70, ER/PR− HER2+ 59 and ER/PR/HER2– 87; Mexico ER/PR+ HER2– 120, ER/PR+ HER2+ 18, ER/PR− HER2+ 9 and ER/PR/HER2– 22.