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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Cancer Prev Res (Phila). 2020 Mar 17;13(5):449–462. doi: 10.1158/1940-6207.CAPR-19-0491

Figure 2. Tumor growth in female progeny with adult BSp (A-BSp), pregestational maternal BSp (P-BSp) and long-term maternal BSp (L-BSp) dietary administrations.

Figure 2.

Female Her2/neu transgenic mice were administered either regular control (AIN-93G) diet or 26% BSp diet from 10 weeks of age until termination of the experiment (A-BSp), from postnatal 3 weeks of age until prior to mating (10 wks) (P-BSp), or until the weaning of their offspring (3 wks) (L-BSp). Weaned female offspring were maintained on the control diet throughout their lifespan until termination of the experiment and monitored for tumor growth weekly. The adult control (A-Control) was applied as the control in A-BSp treatment group. The long-term control (L-Control) was used as the control in P-BSp and L-BSp treatments. A, tumor growth volume; B, tumor incidence; C, tumor latency; D, tumor weight. Columns, mean; Bars, SD; *, P < 0.05; **, P < 0.01, significantly different from the control group.