Table 3.
Prognostic factors for complete remission in autoimmune hepatitis.
| Univariate Cox hazard analysis |
Multivariate Cox hazard analysis |
|||
|---|---|---|---|---|
| Crude HR (95%CI) | P value | Adjusted HR (95%CI) | P value | |
| Age | 1.00 (0.99–1.00) | 0.052 | 1.00 (0.99–1.00) | 0.206 |
| Azathioprine exposure | 0.67 (0.41–1.12) | 0.128 | 0.49 (0.28–0.84) | 0.009∗ |
| Female | 0.72 (0.39–1.33) | 0.294 | - | - |
| BMI | 0.98 (0.90–1.06) | 0.582 | - | - |
| Hypertension | 0.35 (0.12–0.97) | 0.043∗ | 0.16 (0.05–0.54) | 0.003∗ |
| Cirrhosis§ | 0.48 (0.24–0.98) | 0.045∗ | 0.37 (0.18–0.76) | 0.007∗ |
| Child Pugh score | 0.76 (0.50–1.14) | 0.185 | - | - |
| Platelets | 1.00 (0.99–1.00) | 0.076 | - | - |
| Albumin | 1.04 (0.99–1.09) | 0.065 | - | - |
| TB | 1.00 (0.98–1.03) | 0.755 | - | - |
| ALT | 1.00 (0.99–1.00) | 0.072 | - | - |
| AST | 1.00 (0.99–1.00) | 0.078 | - | - |
| ALP | 0.99 (0.99–1.00) | 0.033∗ | 0.99 (0.99–1.00) | 0.050 |
| AST/ALT ratio | 1.00 (0.93–1.07) | 0.953 | ||
| PBC overlap | 0.39 (0.14–1.07) | 0.068 | - | - |
Abbreviations: BMI, body mass index; TB, total bilirubin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; PBC, primary biliary cholangitis.
§
Cirrhosis was diagnosed by ultrasonography.