Table I.
The Localization and mRNA/Protein Expression of LAT1 in Human Tissues According to the Human Protein Atlas (27)
| Tissue | mRNA* | Protein |
|---|---|---|
| Cerebral cortex including endothelial cells and neurons, cerebellum | 15.9–45.8 | medium |
| Olfactory region, hippocampus, amygdala, thalamus, hypothalamus, midbrain, pons and medulla, corpus callosum, spinal cord | 9.6–24.5 | N/A |
| Basal ganglia | 24.5 | low |
| Retina | 34.9 | N/A |
| Thyroid gland | 4.2 | medium |
| Parathyroid and adrenal glands | 1.5–3.2 | high |
| Pituitary gland | 9.0 | N/A |
| Salivary gland and esophagus | 11.5–38.7 | high |
| Oral mucosa | N/A | medium |
| Tongue | 16.7 | N/A |
| Nasopharynx | N/A | medium |
| Bronchus | N/A | high |
| Lung | 3.8 | medium |
| Kidney and urinary bladder | 3.6–11.5 | high |
| Gastrointestinal tract: stomach, duodenum, small intestine, colon, rectum | 3.4–12.7 | high |
| Epididymis, seminal vesicle and prostate | 4.3–30.4 | medium |
| Testis | high | |
| Ovary, endometrium, placenta and breast | 4.3–28.4 | medium |
| Fallopian tube and cervix | 3.3–7.9 | high |
| Heart muscle | 8.2 | high |
| Skeletal muscle | 11.2 | medium |
| Smooth muscle | 4.8 | high |
| Adipose tissue | 8.2 | N/A |
| Liver and gallblader | 9.7 | medium |
| Gallblader | 6.4 | high |
| Skin | 10.7 | medium |
| Lymph node | 11.1 | low |
| Spleen and tonsil | 6.4–15.0 | medium |
| Bone marrow | 71.2 | high |
| Thymus | 3.7 | N/A |
| Appendix | 14.7 | high |
| Blood cells including granulocytes, T- and B-cells, NK cells, dendritic cells | 0.2–15.9 | N/A |
N/A – no data available
*- normalized expression levels.