. 2020 May 6;10:7616. doi: 10.1038/s41598-020-64400-x

Table 1.

Exchanged fragments in MRP1 with the corresponding MRP2 fragments in MRP1/MRP2 chimeras.

Chimera name	Domain	Exchanged amino-acid Fragments
M1	TM5-L0	MRP1 ¹⁶⁸D-²⁸⁰K → MRP2 ¹⁶²N-²⁶⁷Q
M2	L0	MRP1 ²⁸³A-³¹⁶V → MRP2 ²⁷⁰G-³⁰³A
M3	TM6-TM7	MRP1 ³¹⁷L-³⁹⁶K → MRP2 ³⁰⁴L-³⁸³R
M4	ICL5-TM10-TM11	MRP1 ⁴⁹³A-⁶¹⁶L → MRP2 ⁴⁸⁰K-⁶⁰³L
M5	L1	MRP1 ⁸⁶⁹Y-⁹³⁰S → MRP2 ⁸⁵²F-⁹²⁵N
M6	L1-TM12	MRP1 ⁹³¹T-¹⁰¹³K → MRP2 ⁹²⁶V-¹⁰¹¹D
M7	TM14-TM15-ICL7	MRP1 ¹⁰⁸⁵S-¹¹⁹⁰Y → MRP2 ¹⁰⁸³D-¹¹⁸⁸F
M8	TM16-TM17	MRP1 ¹¹⁹¹P-¹²⁷⁰T → MRP2 ¹¹⁸⁹S-¹²⁶⁸V