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. 2020 May 6;10:7661. doi: 10.1038/s41598-020-64633-w

Table 3.

Associations of asthma status in different Grades in school with grade point sum and non-eligibility to upper secondary school (USS).

Grade point sum Unadjusted model Adjusted modela Sibling comparisonb
n β [95% CI] n β [95% CI] Cohen’s d nc β [95% CI] Cohen’s d
Asthma in Grades 7–8
No 539,422 0.0 526,503 0.0 11,225 0.0
Mild/moderate controlled 27,442 3.4 [2.6, 4.1] 26,852 4.6 [4.0, 5.3] 0.07 10,120 0.3 [−0.8, 1.4] 0.00
Severe controlled 897 13.0 [9.2, 16.7] 885 12.5 [9.3, 15.7] 0.20 403 7.3 [2.3, 12.3] 0.12
Mild/moderate uncontrolled 2,627 −14.2 [−16.7, −11.7] 2,553 −6.7 [−8.9, −4.5] 0.11 1,086 −0.5 [−3.9, 2.9] 0.01
Severe uncontrolled 207 0.6 [−8.6, 9.7] 201 4.5 [−3.1, 12.2] 0.07 84 2.9 [−10.2, 15.9] 0.05
Asthma in Grade 9
No 551,128 0.0 537,931 0.0 7,239 0.0
Mild/moderate controlled 16,281 5.8 [4.8, 6.7] 15,957 6.1 [5.3, 6.9] 0.10 6,210 1.0 [−0.4, 2.3] 0.02
Severe controlled 1,294 12.1 [8.9, 15.4] 1,270 10.3 [7.6, 13.0] 0.17 553 1.0 [−3.9, 5.9] 0.02
Mild/moderate uncontrolled 1,657 −17.2 [−20.6, −13.8] 1,605 −9.9 [−12.8, −7.0] 0.16 638 −7.6 [−12.6, −2.6] 0.12
Severe uncontrolled 235 −3.7 [−11.7, 4.3] 231 −2.9 [−9.8, 3.9] 0.05 110 −2.7 [−13.8, 8.4] 0.04
Non-eligibility to USS n OR [95% CI] n OR [95% CI] nc OR [95% CI]
Asthma in Grades 7–8
No 539,422 1.00 526,503 1.00 1,177 1.00
Mild/moderate controlled 27,442 0.82 [0.78, 0.86] 26,852 0.81 [0.77, 0.85] 1,031 1.03 [0.90, 1.18]
Severe controlled 897 0.62 [0.47, 0.83] 885 0.68 [0.51, 0.91] 26 0.71 [0.28, 1.77]
Mild/moderate uncontrolled 2,627 1.40 [1.25, 1.58] 2,553 1.15 [1.01, 1.30] 155 0.73 [0.51, 1.05]
Severe uncontrolled 207 1.03 [0.64, 1.64] 201 0.87 [0.51, 1.48] 9 1.75 [0.56, 5.43]
Asthma in Grade 9
No 551,128 1.00 537,931 1.00 676 1.00
Mild/moderate controlled 16,281 0.77 [0.72, 0.82] 15,957 0.78 [0.73, 0.83] 540 0.95 [0.79, 1.14]
Severe controlled 1,294 0.73 [0.59, 0.91] 1,270 0.81 [0.64, 1.02] 52 1.05 [0.58, 1.91]
Mild/moderate uncontrolled 1,657 1.75 [1.53, 2.00] 1,605 1.44 [1.23, 1.67] 96 1.96 [1.22, 3.14]
Severe uncontrolled 235 1.00 [0.64, 1.56] 231 0.93 [0.57, 1.51] 10 2.67 [0.59, 12.05]

aAdjusted models were adjusted for gender, ADHD, gender x ADHD interaction, mother’s and father’s education and asthma, family income the year the child started school.

bSibling comparisons were adjusted for all familial factors shared by the siblings + gender, ADHD, gender x ADHD interaction and family income the year the child started school.

cNumber of children in pairs discordant for both asthma variable and school performance measure.