Table 4.
Adjusted mean (SE) POMWP AUC(0–120h) (cm) ANCOVA analysis—TS
| Treatment | N | Mean (SD) at baseline | Adjusted mean (SE)a | Comparison vs diclofenac + capsaicin | ||
|---|---|---|---|---|---|---|
| Adjusted mean of difference (SE)a,b | 95% CI | P value | ||||
| Placebo | 75 | 7.20 (1.246) | 4.26 (0.213) | − 0.37 (0.221) | − 0.80, 0.07 | 0.0956 |
| Capsaicin | 223 | 7.22 (1.157) | 3.95 (0.145) | 0.30 (0.157) | − 0.01, 0.61 | 0.0564 |
| Diclofenac | 223 | 7.29 (1.274) | 4.81 (0.145) | − 0.56 (0.157) | − 0.87, − 0.25 | 0.0004 |
| Diclofenac + capsaicin | 225 | 7.28 (1.148) | 4.25 (0.143) | |||
CI confidence interval, FAS full analysis set, POMWP pain on movement worst procedure, SD standard deviation, SE standard error, TS treated set
aModel includes treatment, country, application site, and baseline POMWP
bNegative values are in favor of the combination treatment