Table 4.

Selectivity over histone deacetylases and deubiquitinases compared to pan-DUB inhibitor PR-619.

Compound	% inhibition @ 100 μM		Qualitative pan-DUB inhibition
	HDAC1	HDAC6	@ 10 μM	@ 50 μM
S1th 10	n.i.*	29%	n.i.	n.i.
S1th 11	n.i.	n.i.	n.i.	n.i.
S1th 12	n.i.	36%	n.i.	n.i.
S1th 13	n.i.	19%	n.i.	n.i.
PR-619	54%	49%	+	+++

^*n.i., no inhibition (<10%), + low inhibition, +++ full inhibition.