Fig. 1. Summary of major contributing mechanisms involved in eosinophilic inflammation. PGD2, prostaglandin D2; LTC4, leukotriene C4; Th2, T-helper 2 cells; ILC2, innate lymphoid cell 2; IL, interleukin; DC, dendritic cells; TSLP, thymic stromal lymphopoietin; GM-CSF, granulocyte-macrophage colony-stimulating factor; LTB4, leukotriene B4; PAF, platelet-activating factor; VCAM-1, vascular cell adhesion molecule-1; ICAM-1, intercellular adhesion molecule-1.
