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. 2020 Apr 30;11:275. doi: 10.3389/fendo.2020.00275

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Copyright © 2020 Hankir and Seyfried.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of RYGB and VSG on brown and beige adipose tissue thermogenesis in rodents and humans. The studies discussed in this Review generally show a stimulatory effect of RYGB and VSG on brown and/or beige adipose tissue thermogenesis involving canonical, UCP1-dependent or non-canonical, UCP1-independent mechanisms. cBAT refers to classical BAT which is the interscapular depot in rodents and supraclavicular depot in humans. sWAT refers to subcutaneous WAT which is the inguinal depot in rodents and abdominal depot in humans. vWAT refers to visceral WAT which is the epigonadal depot in rodents and omental depot in humans. Note how sWAT in rodents and vWAT in humans have more browning potential, respectively.