Table 2.
Chromosome cytoband start location | Types of alteration in TADE | ||||
---|---|---|---|---|---|
TADE 1 | TADE 2 | TADE 3 | TADE 4 | TADE 5 | |
1p13.3 (GSTM1) (46) | – | Gain | – | Gain | Gain |
3p21.1 (NEK4) | LOH | LOH | – | – | LOH |
3p21.31 (RASSF1) | LOH | Loss | – | LOH | – |
14q32.33 (LINC00221) | Gain | Gain | – | – | Gain |
22q11.23 (GSTT1) (47) | LOH | LOH | Gain + LOH | LOH | Gain +LOH |
All 5 TADE showed differences in genetic alteration (LOH, gain, gain + LOH, or none) at the same loci.